The University of Oxford’s Jenner Institute and Oxford Vaccine Group have been at the forefront of scientific endeavour to develop vaccines for diseases of major global importance for more than 30 years.
Their ChAdOx1 trials are currently assessing whether the vaccine will be effective in combatting COVID-19.
Oxford launches its first results from the COVID-19 vaccine trial
Interim results of Oxford University's Phase I/II trial of a COVID-19 vaccine were published today in the scientific journal, The Lancet. They indicate no safety concerns, as well as T-cell and antibody responses against the SARS-CoV-2 virus, and neutralising antibody response. The trials will continue, in order to find out whether these responses are the type and strength needed to fight the virus.
Spotlight on Professor Sarah Gilbert
Professor Gilbert joined the Nuffield Department of Medicine at Oxford University in 1994 and became part of the Jenner Institute (within NDM) when it was founded in 2005. Her chief research interest is the development of viral vectored vaccines that work by inducing strong and protective T and B cell responses. She leads the Jenner Institute programme in influenza vaccine development and now also works on vaccines for many different emerging pathogens, including Nipah, MERS, Lassa and CCHF. Working with colleagues in the Jenner Institute research labs, the Clinical Biomanufacturing Facility and Centre for Clinical Vaccinology and Tropical Medicine, all situated on the Old Road Campus in Oxford, she is able to take novel vaccines from design to clinical development, with a particular interest in the rapid transfer of vaccines into GMP manufacturing and first in human trials. She is the Oxford Project Leader for ChAdOx1 nCoV-19.
Spotlight on Professor Andrew J Pollard
Professor Pollard obtained his medical degree at St Bartholomew’s Hospital Medical School, University of London in 1989 and trained in Paediatrics at Birmingham Children’s Hospital, UK, specialising in Paediatric Infectious Diseases at St Mary’s Hospital, London, UK and at British Columbia Children’s Hospital, Vancouver, Canada. He obtained his PhD at St Mary’s Hospital, London, UK in 1999 studying immunity to Neisseria meningitidis (meningitis) in children and proceeded to work on anti-bacterial innate immune responses in children in Canada before returning to his current position at the University of Oxford, UK in 2001.
Spotlight on Professor Adrian Hill
Professor Hill is Lakshmi Mittal and Family Professor of Vaccinology and Director of the Jenner Institute, which focuses on designing and developing vaccines for infectious diseases prevalent in developing countries, such as HIV/AIDS, malaria and tuberculosis. He also heads a group at the Wellcome Trust Centre for Human Genetics which studies genetic susceptibility factors for common bacterial diseases. His own vaccine research programme has developed one of the most promising potential vaccines for malaria which is currently in large scale trials in infants in sub-Saharan Africa. His group led the first clinical trial of an Ebola virus vaccine targeting the outbreak of Ebola in West Africa.
Human trial of new COVID-19 vaccine begins
In April 2020 researchers from Oxford University's Jenner Institute and the Oxford Vaccine Group have begun testing a potential new vaccine for COVID-19 in healthy volunteers.
Spotlight on Professor Teresa Lambe
Professor Lambe’s area of expertise is vaccine development. She is an experienced immunologist who develops vaccines against emerging and outbreak pathogens. She is experienced at progressing preclinical concepts all the way through to clinical assessment. Her team is working on measuring the immune response after vaccination against SARS-CoV-2. This work principally involves measuring the antibody response after vaccination.
Meet our researchers
Professor Green heads the Nuffield Department of Medicine's Clinical Biomanufacturing Facility (CBF). She is the Monsanto Senior Research Fellow at Ex...
Dr Christina Dold has been part of the Oxford Vaccine Group since 2011. She is a senior postdoctoral scientist, specialising in preclinical and Phase...
Richard Tarrant, PhD and BSc, became a Qualified Person (QP) for the Clinical BioManufacturing Facility (CBF) in October 2018.
Emma Bolam is Head of Production at the Jenner Institute’s Clinical BioManufacturing Facility (CBF). She has been a researcher at Oxford for nearly 25...
Dr Sandy Douglas is an academic clinician and holds a Wellcome Trust Postdoctoral Fellowship for Clinicians (i.e. Career Development fellowship). He i...
Professor Gilbert has been a part of Oxford’s vaccine community since 1994, working closely with Professor Adrian Hill, Director of the Jenner Institu...