Showing articles associated with Sandy Douglas
Dr Sandy Douglas is an academic clinician and holds a Wellcome Trust Postdoctoral Fellowship for Clinicians (i.e. Career Development fellowship). He is also a Co-Investigator on the EPSRC funded Future Vaccine Manufacturing Research Hub (Vax-Hub) and hold an MRC grant to develop a novel rabies vaccine and carry out clinical trials.
What is your main area(s) of interest/expertise?
The development of efficient and scalable vaccine manufacturing processes, development of antibody-inducing vaccines against the rabies virus and sporozoite stage of malaria, and the development of vaccine thermostabilisation technologies.
In earlier work, I identified the potential of PfRH5 as an antigen capable of inducing highly potent strain-transcending neutralising antibodies against the disease causing blood-stage of Plasmodium falciparum and demonstrated that PfRH5-based vaccines could achieve in vivo protection against a virulent P. falciparum challenge. These vaccines are now in clinical trials.
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