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John Todd is Professor of Precision Medicine at the University of Oxford, Director of the JDRF/Wellcome Trust Diabetes and Inflammation Laboratory (DIL) in the University’s Wellcome Trust Centre for Human Genetics, and a Senior Investigator of the National Institute for Health Research.

What is your main area(s) of interest/expertise?

Pathogen Evolution and Sequencing

What are you working on right now?

The Wellcome Centre for Human Genetics (WHG) with Christophe Fraser’s group in the Big Data Institute (BDI), have designed and tested high-throughput sequencing tool for 2019-nCoV, based on their SARS experience. The WHG has recently established a major collaboration with the Chinese sequencing company, BGI, which has just announced urgent release of its latest ultra-high-throughput sequencer and a 2019-nCoV RT PCR kit. Miles Carroll who recently joined NDM on partial secondment from Public Health England will assist in getting samples. Establishing safe local protocols is going to be a priority. A number of groups in Oxford are contributing to the disease modelling, development of anti-viral agents, structural determination of key nCoV proteins, vaccine development and identification of therapeutic monoclonal antibodies against the virus.

Why is Oxford a good place to work in this field of research?

Oxford has incredible depth and width in research and the translation of scientific discoveries into approaches that benefit human health.

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John Todd
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